The role of atypical enteropathogenic Escherichia coli (EPEC) in childhood diarrhea is controversial. The aim of the present study was to search for genes linked with diarrhea in atypical EPEC strains from a case-control study among Norwegian children. Using DNA microarray analysis, genomic DNAs from strains isolated from children with ( n = 37) and without ( n = 20) diarrhea were hybridized


After entry into the nucleus, herpes simplex virus (HSV) DNA is coated with repressive proteins and becomes the site of assembly of nuclear domain 10 (ND10) bodies. These small (0.1-1 μM) nuclear structures contain both constant [e.g., promyelocytic leukemia protein (PML), Sp100, death-domain associ …

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The largest, PML I, consists of nine exons (29–31). PML −/ cell clones were generated from HEp-2 cells by transfection of clus tered regularly interspaced short palindromic repeats [clustered regularly interspaced short palin- Quantitation of the number of organisms in the Lpf mutant biofilm confirmed that slightly fewer lpf mutant organisms were able to grow on HEp-2 cells after 24 h (Fig. 3). Thus, S. enterica serovar Typhimurium mutants defective in the production of Pef, Tafi, and Lpf fimbriae were substantially decreased in their ability to form biofilms on HEp-2 tissue culture cells compared to the parent strain, BJ2710. acterized. The long polar fimbriae (Lpf) are encoded by the lpfABCDE genes and have been implicated in the colonization of the murine intestinal mucosa (3, 5, 36).

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If you don't know the Document ID, use Advanced Search. Salmonella enterica serovar Typhimurium requires the Lpf, Pef, and Tafi fimbriae for biofilm formation on HEp-2 tissue culture cells and chicken intestinal epithelium. Infect Immun 2006 Jun;74(6):3156-69 Date 05/23/2006 Pubmed ID 16714543 Pubmed Central ID PMC1479237 DOI 10.1128/IAI.01428-05 Scopus ID 2-s2.0-33646910168 82 Citations Abstract 2019-10-25 · En español l How’s your bilirubin level?

Hep lpf 113-21

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The Long Polar Fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. . Studies have demonstrated the presence of lpf genes in several pathogenic E. coli strains and classification of variants based on polymorphisms in the lpfA1 and lpfA2 genes has been a Time constant (Secondary LPF) 113–21.
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Figure 21 Cell adhesion assay in the presence of RGD and/or heparin (hep) . conformation kept open by the inhibitor Ac-P(DON)LPF-NH2. 113-21.
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